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Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum

By Wenhui Wu, Keiji Hasumi, Hui Peng, Xianwen Hu, Xichang Wang and Bin Bao

Abstract

Two of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy. The two compounds were identified to be 1-O-palmitoyl-2-O-oleoyl-3-O-(α-D-glucopyranosyl) –glycerol (POGG) and 1-O-myristoyl-2-O-oleoyl-3-O-(α-D-glucopyranosyl) – glycerol (MOGG) which were obtained from Sargassum fulvellum for the first time. POGG and MOGG showed fibrinolytic activity in the reaction system of pro-u-PA and plasminogen

Topics: Article
Publisher: Molecular Diversity Preservation International
OAI identifier: oai:pubmedcentral.nih.gov:2707035
Provided by: PubMed Central

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