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Fibrinolytic Compounds Isolated from a Brown Alga, Sargassum fulvellum

By Wenhui Wu, Keiji Hasumi, Hui Peng, Xianwen Hu, Xichang Wang and Bin Bao


Two of bioactive natural products were founded in a brown alga, Sargassum fulvellum. After isolation and purification, the molecular structures of these two products were investigated by NMR spectroscopy and GC-mass spectroscopy. The two compounds were identified to be 1-O-palmitoyl-2-O-oleoyl-3-O-(α-D-glucopyranosyl) –glycerol (POGG) and 1-O-myristoyl-2-O-oleoyl-3-O-(α-D-glucopyranosyl) – glycerol (MOGG) which were obtained from Sargassum fulvellum for the first time. POGG and MOGG showed fibrinolytic activity in the reaction system of pro-u-PA and plasminogen

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Publisher: Molecular Diversity Preservation International
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Provided by: PubMed Central

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