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Polyclonal B Cell Differentiation and Loss of Gastrointestinal Tract Germinal Centers in the Earliest Stages of HIV-1 Infection

By Marc C. Levesque, M. Anthony Moody, Kwan-Ki Hwang, Dawn J. Marshall, John F. Whitesides, Joshua D. Amos, Thaddeus C. Gurley, Sallie Allgood, Benjamin B. Haynes, Nathan A. Vandergrift, Steven Plonk, Daniel C. Parker, Myron S. Cohen, Georgia D. Tomaras, Paul A. Goepfert, George M. Shaw, Jörn E. Schmitz, Joseph J. Eron, Nicholas J. Shaheen, Charles B. Hicks, Hua-Xin Liao, Martin Markowitz, Garnett Kelsoe, David M. Margolis and Barton F. Haynes

Abstract

Studying the effects of early HIV infection on human antibody responses, M. Anthony Moody and colleagues find rapid polyclonal B cell differentiation and structural damage to gut-associated lymphoid tissue

Topics: Research Article
Publisher: Public Library of Science
OAI identifier: oai:pubmedcentral.nih.gov:2702159
Provided by: PubMed Central

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