(2006). A functional genetic screen identifies TFE3 as a gene that confers resistance to the anti-proliferative effects of the retinoblastoma protein and transforming growth factor-beta.
(2008). CpG island methylator phenotype (CIMP) in cancer: causes and implications. Cancer Lett
(2001). ER: Epigenetic inactivation of the RASSF1A 3p21.3 tumor suppressor gene in both clear cell and papillary renal cell carcinoma. Cancer Res
(2008). ER: Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma.
(2002). ER: Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease. Cancer Res
(1998). ER: Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis. Genes Chromosomes Cancer
(1994). ER: Molecular genetic investigation of sporadic renal cell carcinoma: analysis of allele loss on chromosomes 3p, 5q, 11p, 17 and 22.
(2003). ER: Multigene methylation analysis of Wilms' tumour and adult renal cell carcinoma. Oncogene
(2005). ER: Tumor suppressor activity and epigenetic inactivation of hepatocyte growth factor activator inhibitor type 2/SPINT2 in papillary and clear cell renal cell carcinoma. Cancer Res
(2007). Gene methylation and early detection of genitourinary cancer: the road ahead. Nat Rev Cancer
(1994). Identification of the von Hippel-Lindau disease tumor suppressor gene.
(2006). JB: High-throughput DNA methylation profiling using universal bead arrays. Genome Res
(2007). Jerónimo C: Quantitative promoter methylation analysis of multiple cancer-related genes in renal cell tumors.
(2006). KT: Examination of a CpG island methylator phenotype and implications of methylation profiles in solid tumors. Cancer Res
(1994). Linehan WM: Mutations of the VHL tumour suppressor gene in renal carcinoma.
(2008). LS: Kidneytargeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
(2003). Ohno S: Loss of von HippelLindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor. Oncogene
(2006). PJ: Genetic and epigenetic analysis of von Hippel-Lindau (VHL) gene alterations and relationship with clinical variables in sporadic renal cancer. Cancer Res
(2004). Promoter hypermethylation profile of kidney cancer. Clin Cancer Res
(2006). PW: CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer. Nat Genet