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Influence of the JAK2 V617F mutation and inherited thrombophilia on the thrombotic risk among patients with essential thrombocythemia

By Valerio De Stefano, Tommaso Za, Elena Rossi, Alessia Fiorini, Angela Ciminello, Claudia Luzzi, Patrizia Chiusolo, Simona Sica and Giuseppe Leone

Abstract

The role of JAK2 mutations in the thrombotic risk associated with essential thrombocythemia has been unclear. In this study, the authors show an effect of the mutation that is most clearly seen in young patients and when acting in combination with another thrombotic risk factor, factor V Leiden

Topics: Brief Reports
Publisher: Ferrata Storti Foundation
OAI identifier: oai:pubmedcentral.nih.gov:2675688
Provided by: PubMed Central
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