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Preferential expansion of human umbilical cord blood-derived CD34-positive cells on major histocompatibility complex-matched amnion-derived mesenchymal stem cells

By Tomomi Mizokami, Hiroko Hisha, Satoshi Okazaki, Takashi Takaki, Xiao-Li Wang, Chang-Ye Song, Qing Li, Junko Kato, Naoki Hosaka, Muneo Inaba, Hideharu Kanzaki and Susumu Ikehara


In vitro expansion of human hematopoietic stem cells has remained cumbersome. This paper demonstrates that umbilical cord blood-derived lineage negative/CD34-positive cells can selectively expand in vitro when cultured on autologous amnion-derived adherent cells

Topics: Original Article
Publisher: Ferrata Storti Foundation
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Provided by: PubMed Central
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