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Expression of thymidine kinase mediated by a novel non-viral delivery system under the control of vascular endothelial growth factor receptor 2 promoter selectively kills human umbilical vein endothelial cells

By Ying Wang, Hui-Xiong Xu, Ming-De Lu and Qing Tang

Abstract

AIM: To investigate the killing efficiency of a recombinant plasmid containing a thymidine kinase (TK) domain insert driven by the vascular endothelial growth factor receptor 2 (VEGFR2) promoter (KDR) on vascular endothelial cells

Topics: Basic Research
Publisher: The WJG Press and Baishideng
OAI identifier: oai:pubmedcentral.nih.gov:2675118
Provided by: PubMed Central
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