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On the Adaptive Design Rules of Biochemical Networks in Evolution

By Bor-Sen Chen, Wan-Shian Wu, Wei-Sheng Wu and Wen-Hsiung Li

Abstract

Biochemical networks are the backbones of physiological systems of organisms. Therefore, a biochemical network should be sufficiently robust (not sensitive) to tolerate genetic mutations and environmental changes in the evolutionary process. In this study, based on the robustness and sensitivity criteria of biochemical networks, the adaptive design rules are developed for natural selection in the evolutionary process. This will provide insights into the robust adaptive mechanism of biochemical networks in the evolutionary process

Topics: Original Research
Publisher: Libertas Academica
OAI identifier: oai:pubmedcentral.nih.gov:2674634
Provided by: PubMed Central
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