(2006). A: Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of
(1995). A: Point mutations in the dihydrofolate reductase thymidylate synthase gene and pyrimethamine and cycloguanil resistance in Plasmodium falciparum. Mol Biochem Parasitol
(1998). AF: Allelicexchange at the endogenous genomic locus in Plasmodium falciparum proves the role of dihydropteroate synthase in sulfadoxineresistant malaria.
(2003). AF: Analysis Pfcrt, Pfmdr1, dhfr, and dhps mutations and drugs sensitivities in P. falciparum isolates from patients in Vietnam before and after treatment with artemisinin. Am Soc Trop Med Hyg
(2000). AF: Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum. Nature
(1997). Cowman AF: Mutations in dihydropteroate synthase are responsible for sulfone and sufonamide resistance in Plasmodium falciparum. Proc Natl Acad Sci USA
(1998). DC: Plasmodium falciparum: Detection of polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes by PCR and restriction digestion. Exp Parasitol
(2002). do Rosário VE, Cravo P: Molecular characterisation of drug-resistant Plasmodium falciparum from Thailand. Malar J
(1997). Doumbo OK: Mutations in Plasmodium falciparum difydrofolate reductase and dihydropteroate synthase and epidemiologic patterns of pyrimethamine-sulfadoxine use and resistance.
(2000). East Timor Health Sector Situation report. World Health Organ East Timor
(2000). Edstein MD: Efficacy of cloroquine in the treatment of uncomplicated Plasmodium falciparum infection in East Timor,
(2006). Efficacy of sulfadoxine-pyrimethamine in the treatment of uncomplicated P. falciparum malaria in East Timor. Am J Trop Med Hyg
(2007). F: Therapeutic efficacy of sulfadoxine-pyrimethamine and the prevalence of molecular markers of resistance in under 5-years olds in Brazzaville, Congo. Trop Med Int Health
(2001). Fidock DA: A molecular marker for surveillance of chloroquine-resistant falciparum malaria. NEJM
Foote SJ: Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum.
(2001). Growing plains of East Timor: health of an infant nation. The Lancet
(2001). History and importance antimalarial drug resistance. Trop Med Int Health
(1993). Identification of the four human malaria parasite species in field samples by the polymerase chain reaction and detection of a high prevalence of mixed infections. Mol Biochem Parasitol
(1997). JE: Resistance to antiolates in Plasmodium falciparum monitored by sequence analysis of dihydropteroate synthase and dihydrofolate reductase alleles in a large number of field samples of diverse origins. Mol Biochem Parasitol
(1993). KN: High sensitivity of detection of human malaria parasites by the use of nested polymerase chain reaction. Mol Biochem Parasitol
(2000). Malaria Consortium, RBM Complex Emergency Malaria Data Base East Timor. World Organ Health Geneva
(2003). Malaria Control in Complex Emergencies: the example of East Timor. Trop Med Int Health
(1999). Malaria Epidemiological Profile – East and West Timor. World Health Organ Geneva
(2003). Monitoring antimalarial drug resistance: making the most of the tools at hand.
(2002). Pfmdr 1 alleles and response to ultralow-dose mefloquine treatment in Gabonese patients. Antimicrob Agents Chemother
(2003). Plowe CV: Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi. J Infect Dis
(2005). Reeder JC: Molecular epidemiology of Plasmodium falciparum resistance to antimalarial drugs in Indonesia. Am J Trop Med Hyg
(2003). Shankar AH: Frequency distribution on antimalarial drug-resistant alleles among isolates of P. falciparum in Purworejo District, Central Java Province, Indonesia. Am J Trop Med Hyg
(1999). Sonnenberg FV: Plasmodium falciparum resistance to sulfadoxyne/pyrimethamine in Uganda: correlation with polymorphisms in the dehidrofolate reductase and dihydropterate synthetase genes. Am J Trop Med Hyg
(2005). Wellems TE: Decreased prevalence of the Plasmodium falciparum chloroquine resistance transporter 76T marker associated with cessation of choroquine use against P. falciparum malaria in Hainan, people's Republic of China. Am J Trop Med Hyg
Wellems TE: Evidence that a point mutation in dihydrofolate reductase-thymidylate synthase confers resistance to pyrimethamine in falciparum malaria.
(1984). WHO: Advances in malaria chemotherapy. WHO Technical Reports Volume 711. World Health Organ Geneva;
(2000). WM: Towards an understanding of the mechanism of pyrimethamine-sulfadoxine resistance in P. falciparum: genotyping of dihydrofolate reductase and dihydropteroate synthase of Kenyan parasites. Am Soc Microbiol