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Evaluation of Antibodies against Different Epstein-Barr Virus Nuclear Antigen 1 Peptides in Diagnosis of Nasopharyngeal Carcinoma▿

By Ai-Di Gu, Hao-Yuan Mo, Jin-Xin Bei, Yan-Bo Xie, Li-Zhen Chen, Qi-Sheng Feng, Tiebang Kang and Yi-Xin Zeng

Abstract

Epstein-Barr virus nuclear antigen 1 (EBNA1) is a protein expressed consistently in nasopharyngeal carcinoma (NPC). Although antibody levels against three different EBNA1 peptides were all high in NPC patients, the correlation between any two biomarkers was low. Therefore, the selection of distinct EBNA1 peptides could render different results in serological detection for individuals with NPC

Topics: Clinical Laboratory Immunology
Publisher: American Society for Microbiology (ASM)
OAI identifier: oai:pubmedcentral.nih.gov:2668280
Provided by: PubMed Central
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