Skip to main content
Article thumbnail
Location of Repository

Electron Capture Dissociation and Collision-Induced Dissociation of Metal Ion (Ag+, Cu2+, Zn2+, Fe2+, and Fe3+) Complexes of Polyamidoamine (PAMAM) Dendrimers

By Malgorzata A. Kaczorowska and Helen J. Cooper


The electron capture dissociation (ECD) and collision-induced dissociation (CID) of complexes of polyamidoamine (PAMAM) dendrimers with metal ions Ag+, Cu2+, Zn2+, Fe2+, and Fe3+ were determined by Fourier transform ion cyclotron resonance mass spectrometry. Complexes were of the form [PD + M + mH]5+ where PD = generation two PAMAM dendrimer with amidoethanol surface groups, M = metal ion, m = 2–4. Complementary information regarding the site and coordination chemistry of the metal ions can be obtained from the two techniques. The results suggest that complexes of Fe3+ and Cu2+ are coordinated via both core tertiary amines, whereas coordination of Ag+ involves a single core tertiary amine. The Zn2+ and Fe2+ complexes do not appear to involve coordination by the dendrimer core

Topics: Article
Publisher: Springer
OAI identifier:
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.