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Simple molecular networks that respond optimally to time-periodic stimulation

By Axel Cournac and Jacques-Alexandre Sepulchre
Topics: Research Article
Publisher: BioMed Central
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Provided by: PubMed Central
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    1. (1986). A mechanism for exact sensory adaptation based on receptor modification.
    2. (2008). A: The frequency dependence of osmo-adaptation in Saccharomyces cerevisiae. Science
    3. (2005). An evolutionary and functional assessment of regulatory network motifs. Genome Biol
    4. (2006). An Introduction to Systems Biology Chapman & Hall/CRC;
    5. (2003). Arkin AP: Motifs, modules and games in bacteria. Curr Opin Microbiol
    6. Biochemical Oscillations and Cellular Rhythms: The molecular bases of periodic and chaotic behaviour Cambridge
    7. (2000). Construction of a genetic toggle switch in Escherichia coli. Nature
    8. (1981). DE: An amplified sensitivity arising from covalent modification in biological systems.
    9. (2005). Elowitz MB: Gene regulation at the single-cell level. Science
    10. (1972). ER: Long-Term Habituation of a Defensive Withdrawal Reflex in Aplysia. Science
    11. (2007). Gimsa U: Deep brain stimulation in a rat model modulates TH, CaMKIIa and Homer1 gene expression.
    12. (1989). Goldbeter A: Frequency specificity in intercellular communication. Influence of patterns of periodic signaling on target cell responsiveness.
    13. (1992). Goldbeter A: Protein phosphorylation driven by intracellular calcium oscillations: a kinetic analysis. Biophys Chem
    14. (2007). HS: Cell surface receptors for signal transduction and ligand transport: a design principles study. PLoS Comput Biol
    15. (2007). JH: Dynamics of a minimal model of interlocked positive and negative feedback loops of transcriptional regulation by cAMP-response element binding proteins.
    16. (1998). JH: Frequency selectivity, multistability, and oscillations emerge from models of genetic regulatory systems.
    17. (2003). Koninck PD: Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations: a simple model. Cell Calcium
    18. (2000). Leibler S: A synthetic oscillatory network of transcriptionnal regulators.
    19. (2000). Leibler S: Circadian clocks limited by noise. Nature
    20. (1998). Lewis RS: Calcium oscillations increase the efficiency and specificity of gene expression.
    21. (2004). Loros JJ: The neurospora circadian system.
    22. (2008). Merajver SD: A hidden feedback in signaling cascades is revealed. PLoS Comput Biol
    23. (2006). Mink JW: Deep brain stimulation. Annu Rev Neurosci
    24. (2007). Mirny LA: Operating Regimes of Signaling Cycles: Statics, Dynamics, and Noise Filtering. PLoS Comput Biol
    25. (1990). MJ: Minimal model for signalinduced Ca2+ oscillations and for their frequency encoding through protein phosphorylation.
    26. (2006). ML: Frequency domain analysis of noise in simple gene circuits. Chaos
    27. (2000). Negative feedback and ultrasensitivity can bring about oscillations in the mitogen-activated protein kinase cascades.
    28. (2003). Ninfa AJ: Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli. Cell
    29. (2006). Oscillations and variability in the p53 system. Mol Syst Biol
    30. (2006). Poyatos JF: Dynamical principles of two-component genetic oscillators. PLoS Comput Biol
    31. (2007). Receptor downregulation and desensitization enhance the information processing ability of signalling receptors.
    32. (2002). Sari T: A class of piecewise linear differential equations arising in biological models. Dyn Syst
    33. (2006). Scholarpedia
    34. (1998). Sensitivity of CaM kinase II to the frequency of Ca2+ oscillations. Science
    35. (2008). Signal duration and the time scale dependence of signal integration in biochemical pathways.
    36. (2008). Signal processing by the HOG MAP kinase pathway.
    37. (2005). Steady states and oscillations in the p53/Mdm2 network. Cell Cycle
    38. (1995). T: CREB as a memory modulator: induced expression of a dCREB2 activator isoform enhances long-term memory in Drosophila. Cell
    39. (2002). TA: Mathematical models of protein kinase signal transduction. Mol Cell
    40. (2002). The dynamics of cell cycle regulation. Bioessays
    41. (2006). The incoherent feedforward loop accelerates the response-time of the gal system of Escherichia coli.
    42. (1973). The logical analysis of continuous, non-linear biochemical control networks.
    43. (2004). The molecular biology of memory storage: a dialog between genes and synapses. Biosci Rep
    44. (2005). Wong WH: The use of oscillatory signals in the study of genetic networks.

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