(2006). Double-blind randomized controlled clinical trial of the interleukin-6 receptor antagonist, tocilizumab, in European patients with rheumatoid arthritis who had an incomplete response to methotrexate. Arthritis Rheum
(1991). Effects of cytokine combinations on acute phase protein production in two human hepatoma cell lines.
(1994). Effects of recombinant human interleukin-6 in cancer patients: A phase I–II study.
(1989). Elevation of serum interleukin 6 prior to acute phase proteins on the inflammation by surgical operation. Clin Immunol Immunopathol
Essential involvement of IL-6 in the skin wound-healing process as evidenced by delayed wound healing in IL-6-deficient mice.
Improvement in Castleman’s disease by humanized anti-interleukin-6 receptor antibody therapy.
(2006). Infection and musculoskeletal conditions: bacterial and opportunistic infections during anti-TNF therapy. Best Pract Res Clin Rheumatol
Infliximb and its impact on surgical outcomes in rheumatoid arthritis. Ann Theum Dis 2005;64(Suppl III):465.
(2002). Influence of steroids and methotrexate on wound complications after elective rheumatoid hand and wrist surgery.
Interferon b 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocytestimulating factor and regulates the major acute phase protein response in liver cells.
Interleukin-6 and perioperative thermoregulation and HPA-axis activation.
Interleukin-6 treatment augments cutaneous wound healing in immunosuppressed mice.
(1992). Interleukin6 as a new indicator of inflammatory status: detection of serum levels of interleukin-6 and C-reactive protein after surgery. Surgery
Invited review: cytokine regulation of fever: studies using gene knockout mice.
(2005). Outcome of total hip replacement in rheumatic arthritis. Ortop Traumatol Rehabil
(2003). Overexpressed nuclear factor-kB can participate in endogenous C-reactive protein induction, and enhances the effect of C/EBP beta and signal transducer and activator of trabscription-3. Immunology
Phase I trial of subcutaneous interleukin-6 in patients with advanced malignancies. J Clin Oncol 1993;11:499–506. Extended report Ann Rheum Dis 2009;68:654–657.
The Kudo total elbow arthroplasty in patients with rheumatoid arthritis.
(2004). Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum
(2005). Tumor necrosis factor a antagonists and early postoperative complications in patients with inflammatory joint disease undergoing elective orthopedic surgery. Ann Rheum Dis