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Epistatic Effects Contribute to Variation in BMD in Fischer 344 × Lewis F2 Rats

By Daniel L Koller, Lixiang Liu, Imranul Alam, Qiwei Sun, Michael J Econs, Tatiana Foroud and Charles H Turner


To further delineate the factors underlying the complex genetic architecture of BMD in the rat model, a genome screen for epistatic interactions was conducted. Several significant interactions were identified, involving both previously identified and novel QTLs

Topics: Original Articles
Publisher: Amer Soc Bone & Mineral Res.
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Provided by: PubMed Central
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