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Two Clinical Strains of Klebsiella pneumoniae Carrying Plasmid-Borne blaIMP-4, blaSHV-12, and armA Isolated at a Pediatric Center in Shanghai, China▿

By Ying Liu, Bei Zhang, Qing Cao, Weichun Huang, Lisong Shen and Xuan Qin


Two cases of pulmonary infection due to strains of multidrug-resistant Klebsiella pneumoniae were investigated. Beta-lactamase determinants, such as blaIMP-4 and blaSHV-12, and the 16S rRNA methyltransferase-encoding gene armA were detected in these plasmid-bearing organisms. The integron-borne blaIMP-4 and armA contained intervening sequences highly related to those of a Vibrio cholerae O139 plasmid found in Hangzhou, China

Topics: Mechanisms of Resistance
Publisher: American Society for Microbiology (ASM)
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Provided by: PubMed Central
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