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Voriconazole Use for Endemic Fungal Infections▿

By Alison Freifeld, Laurie Proia, David Andes, Larry M. Baddour, Janis Blair, Brad Spellberg, Sandra Arnold, Arnold Lentnek and L. Joseph Wheat


In a retrospective review of 24 patients with histoplasmosis, blastomycosis, or coccidioidomycosis treated with voriconazole (most for salvage therapy), the outcome was favorable (improved or stable) for 22 (95.8%) within 2 months of starting voriconazole and for 20 (83.3%) at the last follow-up. Prospective studies are required to determine its role in the treatment of endemic mycoses

Topics: Clinical Therapeutics
Publisher: American Society for Microbiology (ASM)
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Provided by: PubMed Central
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