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Inhibition of Spleen Tyrosine Kinase Prevents Mast Cell Activation and Airway Hyperresponsiveness

By Shigeki Matsubara, Guiming Li, Katsuyuki Takeda, Joan E. Loader, Polly Pine, Esteban S. Masuda, Nobuaki Miyahara, Satoko Miyahara, Joseph J. Lucas, Azzeddine Dakhama and Erwin W. Gelfand

Abstract

Rationale: Spleen tyrosine kinase (Syk) is important for Fc and B-cell receptor–mediated signaling

Topics: B. Asthma and Allergy
Publisher: American Thoracic Society
OAI identifier: oai:pubmedcentral.nih.gov:2662982
Provided by: PubMed Central
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