Skip to main content
Article thumbnail
Location of Repository

Inhibition of flucloxacillin tubular renal secretion by piperacillin

By Cornelia B Landersdorfer, Carl M J Kirkpatrick, Martina Kinzig, Jürgen B Bulitta, Ulrike Holzgrabe and Fritz Sörgel

Abstract

WHAT IS ALREADY KNOWN ABOUT THIS SUBJECTMost β-lactams are excreted by filtration and to a greater extent by tubular secretion, which is a capacity-limited saturable pathway.Pharmacokinetic interactions between co-administered β-lactams have been frequently reported; however, their mechanism and possible clinical benefits are not well defined.We are not aware of the interaction between piperacillin and flucloxacillin being reported in the literature

Topics: Drug Interactions
Publisher: Blackwell Science Inc
OAI identifier: oai:pubmedcentral.nih.gov:2661980
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.