Skip to main content
Article thumbnail
Location of Repository

Sepsis Alters the Megakaryocyte–Platelet Transcriptional Axis Resulting in Granzyme B–mediated Lymphotoxicity

By Robert J. Freishtat, JoAnne Natale, Angela S. Benton, Joanna Cohen, Matthew Sharron, Andrew A. Wiles, Wai-Man Ngor, Bahar Mojgani, Margaret Bradbury, Andrew Degnan, Reecha Sachdeva, Lindsay M. DeBiase, Svetlana Ghimbovschi, Matthew Chow, Clarice Bunag, Ervand Kristosturyan and Eric P. Hoffman

Abstract

Rationale: Sepsis-related mortality results in part from immunodeficiency secondary to profound lymphoid apoptosis. The biological mechanisms responsible are not understood

Topics: C. Critical Care
Publisher: American Thoracic Society
OAI identifier: oai:pubmedcentral.nih.gov:2654976
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.