Skip to main content
Article thumbnail
Location of Repository

Clinical variables and implications of the personality on the outcome of bipolar illness: a pilot study

By Nieves Casas-Barquero, Olga García-López, Pedro Fernández-Argüelles and Manuel Camacho-Laraña

Abstract

Outcome in bipolar patients is affected by comorbidity. Comorbid personality disorders are frequent and may complicate the course of bipolar illness. This pilot study examined a series of 40 euthymic bipolar patients (DSM-IV criteria) (bipolar I disorder 31, bipolar II disorder 9) to assess the effect of clinical variables and the influence of comorbid personality on the clinical course of bipolar illness. Bipolar patients with a diagnosis of comorbid personality disorder (n = 30) were compared with “pure” bipolar patients (n = 10) with regard to demographic, clinical, and course of illness variables. Comorbid personality disorder was diagnosed in 75% of patients according to ICD-10 criteria, with obsessive-compulsive personality disorder being the most frequent type. Sixty-three per cent of subjects had more than one comorbid personality disorder. Bipolar patients with and without comorbid personality disorder showed no significant differences regarding features of the bipolar illness, although the group with comorbid personality disorder showed a younger age at onset, more depressive episodes, and longer duration of bipolar illness. In subjects with comorbid personality disorders, the number of hospitalizations correlated significantly with depressive episodes and there was an inverse correlation between age at the first episode and duration of bipolar illness. These findings, however, should be interpreted taking into account the preliminary nature of a pilot study and the contamination of the sample with too many bipolar II patients

Topics: Original Research
Publisher: Dove Medical Press
OAI identifier: oai:pubmedcentral.nih.gov:2654634
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    Citations

    1. (2001). Affective instability and impulsivity in borderline personality and bipolar II disorders: similarities and differences.
    2. (2007). Alcoholism and anxiety in bipolar illness: Differential lifetime anxiety comorbidity in bipolar I women with and without alcoholism.
    3. (1995). Alcoholism in manicdepressive (bipolar) illness: familial illness, course of illness, and the primary-secondary distinction.
    4. (2003). Bipolar comorbidity: from diagnostic dilemmas to therapeutic challenge.
    5. (2000). Bipolar II disorder and its premorbid personality.
    6. (2001). Clinical correlates of psychiatric comorbidity in bipolar I patients. Bipolar Disord,
    7. (2000). Clinical factors associated with treatment noncompliance in euthymic bipolar patients.
    8. (1997). Curso y evolución del trastorno bipolar.
    9. (2006). Descriptive and longitudinal observations on the relationship of borderline personality disorder and bipolar disorder.
    10. (2004). Diagnosing and treating comorbid (complicated) bipolar disorder.
    11. (2001). Do patients with borderline personality disorder belong to the bipolar spectrum? J Affect Disord,
    12. (2003). Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network.
    13. (2003). Frequency of comorbid personality disorders in bipolar and unipolar affective disorders. Compr Psychiatry,
    14. (2006). Illness course, comorbidity, gender, and suicidality in patients with bipolar disorder.
    15. (2002). Impact of axis II comorbidity on the course of bipolar illness in men: a retrospective chart review. Bipolar Disord,
    16. (2002). Lista integrada para el diagnóstico de los trastornos de personalidad (LIDTP). An Psiquiatr,
    17. (2003). Longitudinal outcome in patients with bipolar disorder assessed by life-charting is infl uenced by DSM-IV personality disorder symptoms. Bipolar Disord,
    18. (2006). Medical comorbidity in bipolar disorder: implications for functional outcomes and health service utilization. Psychiatr Serv,
    19. (2001). Personality disorders in bipolar and depressive disorders.
    20. (1986). Personality of recovered patients with bipolar affective disorder.
    21. (2006). Pharmacological treatment of psychiatric comorbidity in bipolar disorder: a review of controlled trials. Bipolar Disord,
    22. (2000). Predictors of work adjustment in bipolar I patients: a naturalistic longitudinal follow-up.
    23. (1999). Prevalence of axis II comorbidity in bipolar patients with and without alcohol use disorders. Ann Clin Psychiatry,
    24. (2006). Relationship of borderline personality disorder and bipolar disorder.
    25. (2003). The comorbidity of bipolar disorder and axis II personality disorders: prevalence and clinical correlates. Bipolar Disord,

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.