Skip to main content
Article thumbnail
Location of Repository

Haplotype frequencies in a sub-region of chromosome 19q13.3, related to risk and prognosis of cancer, differ dramatically between ethnic groups

By Mikkel H Schierup, Thomas Mailund, Heng Li, Jun Wang, Anne Tjønneland, Ulla Vogel, Lars Bolund and Bjørn A Nexø
Topics: Research Article
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

Suggested articles


  1. (2006). O: ERCC1, XPD and RAI mRNA levels in lymphocytes are not associated with lung cancer risk in a prospective study of Danes. Mutation research
  2. (2007). Nexo BA: Expression of the RAI gene is conducive to apoptosis: studies of induction and interference. Experimental cell research
  3. (1999). Nexo BA: Polymorphisms in the DNA repair gene XPD: correlations with risk and age at onset of basal cell carcinoma. Cancer Epidemiol Biomarkers Prev
  4. (2003). Tjonneland A: A specific haplotype of single nucleotide polymorphisms on chromosome 19q13.2-3 encompassing the gene RAI is indicative of post-menopausal breast cancer before age 55. Carcinogenesis
  5. (2002). Nexo BA: Association of chromosome 19q13.2-3 haplotypes with basal cell carcinoma: tentative delineation of an involved region using data for single nucleotide polymorphisms in two cohorts. Carcinogenesis
  6. (2006). Kure EH: Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study. BMC cancer
  7. (2001). Nexo BA: Polymorphisms of the DNA repair gene XPD: correlations with risk of basal cell carcinoma revisited. Carcinogenesis
  8. (2004). Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer. Mutation research
  9. (2007). H: A haplotype encompassing the variant allele of DNA repair gene polymorphism ERCC2/XPD Lys751Gln but not the variant allele of Asp312Asn is associated with risk of lung cancer in a northeastern Chinese population. Cancer genetics and cytogenetics
  10. (2008). Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP. BMC medical genetics
  11. (2007). Lillevang ST, Vogel U: Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation.
  12. (2006). Canzian F: Polymorphisms in genes of nucleotide and base excision repair: risk and prognosis of colorectal cancer. Clin Cancer Res
  13. (2006). DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. The New England journal of medicine
  14. (2007). Reynisdottir I, et al.: Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nature Genetics
  15. (2008). Natural selection on genes that underlie human disease susceptibility. Current Biology
  16. (2007). Human evolution: Thrifty genes and the dairy queen. Current Biology
  17. (2007). Adaptive drool in the gene pool. Nature Genetics
  18. (2007). Genetic determinants of hair, eye and skin pigmentation in Europeans. Nature Genetics
  19. (2005). Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics
  20. (2002). The structure of haplotype blocks in the human genome. Science
  21. (2006). Schierup MH: Whole genome association mapping by incompatibilities and local perfect phylogenies.
  22. (2007). A second generation human haplotype map of over 3.1 million SNPs. Nature
  23. (2006). A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase.
  24. (2007). Jobling MA: Challenges in human genetic diversity: demographic history and adaptation. Human Molecular Genetics
  25. (2005). Natural selection on protein-coding genes in the human genome. Nature
  26. (2007). Sunyaev SR: Most rare missense alleles are deleterious in humans: Implications for complex disease and association studies.
  27. (2008). Genome-wide association studies for complex traits: consensus, uncertainty and challenges.

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.