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Aldosterone Antagonists for Preventing the Progression of Chronic Kidney Disease: A Systematic Review and Meta-analysis

By Sankar D. Navaneethan, Sagar U. Nigwekar, Ashwini R. Sehgal and Giovanni F.M. Strippoli


Background and objectives: Addition of aldosterone antagonists (AA) might provide renal benefits to proteinuric chronic kidney disease (CKD) patients over and above the inhibition of renin-angiotensin system blockers (RAS). We evaluated the benefits and harms of adding selective and nonselective AA in CKD patients already on RAS

Topics: Chronic Kidney Disease
Publisher: American Society of Nephrology
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Provided by: PubMed Central
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