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Memoirs of a Reincarnated T Cell

By Joseph G. Crompton, Mahendra Rao and Nicholas P. Restifo

Abstract

In two studies published in this issue of Cell Stem Cell, Nishimura et al. (2013) and Vizcardo et al. (2013) reprogram mature, antigen-specific cytotoxic T cells into induced pluripotent stem cells (iPSCs). The antigen-specific iPSCs can be redifferentiated into “rejuvenated” proliferative T cells and have broad applications for adoptive immunotherapy

Publisher: Elsevier Inc.
Year: 2013
DOI identifier: 10.1016/j.stem.2012.12.009
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