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AAA+ Molecular Machines: Firing on All Cylinders

By Sarah E. Ades

Abstract

AAA+ ATPase protein machines use the power obtained from ATP hydrolysis to remodel macromolecular assemblies in the cell. Recent work in Escherichia coli on the ClpX AAA+ protein reveals fundamental mechanical principles that underlie ClpX motor function

Publisher: Elsevier Ltd.
Year: 2006
DOI identifier: 10.1016/j.cub.2006.01.005
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