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Diffusion-Weighted MR Imaging of Unusual White Matter Lesion in a Patient with Menkes Disease

By Eun Shin Lee, Jae Wook Ryoo, Dae Seob Choi, Jae Min Cho, Soo Hyun Kwon and Hee Suk Shin


We report here on the diffusion-weighted imaging of unusual white matter lesions in a case of Menkes disease. On the initial MR imaging, the white matter lesions were localized in the deep periventricular white matter in the absence of diffuse cortical atrophy. The lesion showed diffuse high signal on the diffusion-weighted images and diffuse progression and persistent hyperintensity on the follow up imaging. Our case suggests that the white matter lesion may precede diffuse cortical atrophy in a patient with Menkes disease

Topics: Case Report
Publisher: The Korean Radiological Society
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Provided by: PubMed Central

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