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Standing Out from the Crowd: Cancer Stem Cells in Hepatocellular Carcinoma

By Bruno Sainz and Christopher Heeschen


Cancer stem cells (CSCs) drive solid tumor formation. In this issue of Cancer Cell, Zhao and colleagues indentify the calcium channel α2δ1 subunit as a new functional hepatocellular carcinoma (HCC) CSC biomarker, which is vital for CSC biology as blocking α2δ1 in combination with doxorubicin treatment hinders HCC tumor formation

Publisher: Elsevier Inc.
Year: 2013
DOI identifier: 10.1016/j.ccr.2013.03.023
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