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Parallel β/α-barrels of α-amylase, cyclodextrin glycosyltransferase and oligo-1,6-glucosidase versus the barrel of β-amylase: Evolutionary distance is a reflection of unrelated sequences

By Štefan Janeček


AbstractThe structures of functionally related β/α-barrel starch hydrolases, α-amylase, β-amylase, cyclodextrin glycosyltransferase and oligo-1,6-glucosidase, are discussed, their mutual sequence similarities being emphasized. Since these enzymes (except for β-amylase) along with the predicted set of more than ten β/α-barrels from the α-amylase enzyme superfamily fulfil the criteria characteristic of the products of divergent evolution, their unrooted distance tree is presented

Publisher: Published by Elsevier B.V.
Year: 1994
DOI identifier: 10.1016/0014-5793(94)01019-6
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