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0118: Right ventricular dysfunction in severe tricuspid regurgitation

By Iskander Slama, Lilia Zakhama, Basma Herbegue, Elhem Boussabah, Saoussen Antit, Mejdi Mimouni, Moez Thameur and Soraya Ben Youssef


IntroductionThe relationship between right ventricular function and severe tricuspid regurgitation is intricate: severe TR can lead to right ventricle dysfunction and changes in right ventricle morphology can aggravate a tricuspid regurgitation.AimEstablish a correlation between regional and global right ventricular (RV) function parameters and TR severity.MethodsForty consecutive patients with TR and left ventricle valve disease were enrolled prospectively (mean age: 54±16 years; 23 males), TR was evaluated according to EACVI recommendations by PISA method. Regional right systolic function assessed by tricuspid annular plane systolic excursion (TAPSE) and systolic tissue Doppler velocity measured at the lateral tricuspid annulus (S’) and global RV function assessed by fractional area change (FAC) were measured for all patients. Patients were divided into two groups according to the severity of TR.ResultsTen patients (25%) had severe TR (G1) and 30 patients (75%) had mild or moderate TR (G2). FAC was lower in G1 compared to G2 (24.7±7.4% vs 40.4±10.1%, p<0.0001; respectively). TAPSE was 14.3±3.6mm in G1 vs 17.7±2.6mm in G2, p?0.002 and S’ was 9.7±1.0cm/s in G1 vs 11.7±1.4cm/s in G2, p<0.0001. There was a significant negative correlation between EROA and FAC, TAPSE and S’ with r=-0.58, p<0.0001; r=-0.48, p= 0.001 and r=-0.69, p<0.0001 respectively.ConclusionRegional and global RV function are impaired alike in severe TR

Publisher: Elsevier Masson SAS.
Year: 2014
DOI identifier: 10.1016/S1878-6480(14)71451-X
OAI identifier:

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