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Non sindromic cleft lip and palate: relationship between sex and clinical extension

By Daniella Reis Barbosa Martelli, Renato Assis Machado, Mário Sérgio Oliveira Swerts, Laíse Angélica Mendes Rodrigues, Sibele Nascimento de Aquino and Hercílio Martelli Júnior


AbstractCleft lip and/or palate represent the most common congenital anomalies of the face.AimDescribe the relation between non sindromic cleft lip and/or palate and sex and severity of the clef in Brazilian population.MethodsConducted cross-sectional study, between the years 2009 and 2011, with a population of 366 patients. Data were analyzed with descriptive statistics and using the multinomial logistic regression with an interval of 95% estimated the chances of the types of cleft lip and/or palate between sex.ResultsAmong the 366 cases of non sindromic cleft lip and/or palate, the more frequent clefts were cleft lip and palate, followed respectively by cleft lip and cleft palate. It is noted that cleft palate were more frequent in females, while the cleft lip and palate and cleft labial predominated in males. The risk of occurrence of cleft lip in relation the cleft palate was 2.19 times in males compared to females. While the risk of cleft lip and palate in relation cleft palate was 2.78 times in males compared to females.ConclusionThis study showed that there were differences in the distribution of the non sindromic cleft lip and/or palate between male and female

Publisher: Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda.
Year: 2012
DOI identifier: 10.5935/1808-8694.20120018
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