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Isolation of a new HIV-2 group in the US

By Stephen M Smith, Deanna Christian, Valéry de Lame, Urvi Shah, Louise Austin, Rajeev Gautam, Aarti Gautam, Cristian Apetrei and Preston A Marx


Human immunodeficiency virus type 2 (HIV-2) emerged following cross-species transmission of simian immunodeficiency virus (SIV) from sooty mangabeys to humans several decades ago. The epidemic groups of HIV-2 have been established in the human population for at least 50 years. However, it is likely that new divergent SIVs can infect humans and lead to new outbreaks. We report the isolation of a new strain of HIV-2, HIV2-NWK08F, from an immunodeficient Sierra Leone immigrant. Health care providers in Sierra Leone and elsewhere need to be alerted that a subtype of HIV-2, which is not detected by PCR for epidemic HIV-2 strains, exists and can lead to immunosuppression

Topics: Correspondence
Publisher: BioMed Central
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Provided by: PubMed Central

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