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Mitochondrial DNA Evidence for a Diversified Origin of Workers Building Mausoleum for First Emperor of China

By Zhi Xu, Fan Zhang, Bosong Xu, Jingze Tan, Shilin Li, Chunxiang Li, Hui Zhou, Hong Zhu, Jun Zhang, Qingbo Duan and Li Jin


Variant studies on ancient DNA have attempted to reveal individual origin. Here, based on cloning sequencing and polymerase chain reaction-restriction fragment length polymorphisms, we analyzed polymorphisms in the first hypervariable region and coding regions of mitochondrial DNA of 19 human bone remains which were excavated from a tomb near the Terra Cotta Warriors and dated some 2,200 years before present. With the aim of shedding light on origins of these samples who were supposed to be workers building the mausoleum for the First Emperor of China, we compared them with 2,164 mtDNA profiles from 32 contemporary Chinese populations at both population and individual levels. Our results showed that mausoleum-building workers may be derived from very diverse sources of origin

Topics: Research Article
Publisher: Public Library of Science
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Provided by: PubMed Central

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