Article thumbnail
Location of Repository

An unusual cause of spontaneous bleeding in the intensive care unit – mastocytosis: a case report

By Martial Koenig, Jérôme Morel, Jacqueline Reynaud, Cécile Varvat and Pascal Cathébras


We report the case of a 39-year old male patient who presented with anaphylactoid shock and diffuse bleeding with prolonged activated partial thromboplastin time at the emergency room. The diagnosis of aggressive mastocytosis was suspected and then confirmed by raised tryptase level and mastocytic infiltration of the bone marrow. The outcome was favorable with supportive measures, antihistamine drugs, and imatinib mesylate

Topics: Case Report
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

Suggested articles


  1. (2007). DD: Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria.
  2. (2008). Fatal bleeding due to heparin like-anticoagulant in a 37-year-old woman suffering from systemic mastocytosis. Clin Appl Thromb Hemost
  3. Metcalfe DD: Mastocytosis. In Clinical Hematology Edited by:
  4. (2003). SL: Effects of human mast cell tryptase and eosinophil granule proteins on the kinetics of blood clotting.

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.