Article thumbnail
Location of Repository

Spontaneous mode non-invasive ventilation fails to treat respiratory failure in a patient with Multi-mincore disease: a case report

By Krishna B Sriram, Andrew Thornton and Ral Antic

Abstract

The increased morbidity and mortality resulting from respiratory failure in patients with neuromuscular disorders and/or kyphoscoliosis can be reversed with non-invasive ventilation. Spontaneous mode bilevel pressure ventilation is preferred to other modes of ventilation, due to relative ease of use, but may not be suitable for all patients. We report a 27-year old woman with Multi-minicore disease whose respiratory failure was refractory to spontaneous mode bilevel pressure ventilation. When we altered settings and provided mandatory inspiratory rise time and respiratory rate, it augmented her respiratory efforts and improved ventilation. Our case report describes the benefit of individualising non-invasive ventilation in the management of respiratory failure due to neuromuscular weakness and kyphoscoliosis

Topics: Case Report
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:2527491
Provided by: PubMed Central

Suggested articles

Citations

  1. (1998). A: Sleep and neuromuscular disease: bilevel positive airway pressure by nasal mask as a treatment for sleep disordered breathing in patients with neuromuscular disease.
  2. (2003). Kyphoscoliotic Ventilatory Insufficiency. Effects of long-term Intermittent Positive-Pressure Ventilation. Chest
  3. (2007). LK: Sleep-Related Hypoventilation/Hypoxemic Syndromes. Chest
  4. (2007). Multi-minicore disease: a rare form of myopathy. Neurol India
  5. (2001). Noninvasive mechanical ventilation improves endurance performance in patients with chronic respiratory failure due to thoracic restriction. Chest
  6. (2005). P: Performance characteristics of 10 home mechanical ventilators in pressure-support mode: A comparative bench study. Chest
  7. (2005). Simonds AK: Randomized controlled trial of non-invasive ventilation for nocturnal hypoventilation in neuromuscular and chest wall disease patients with daytime hypercapnia. Thorax

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.