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Tissue distribution of rat macroglobulins in tumour-bearing rats

By N V Maltseva, R M Zorina, N V Mingaljev, N A Krajushkina, T S Chirikova and N A Zorin


Rat macroglobulins were determined in blood sera and extracts of tissues of intact rats and rats with Walker carcinoma by rocket immunoelectrophoresis. The serum levels of α1-macroglobulin (α1MG) α2-macroglobulin (α2MG) and pregnancy-associated α1-glycoprotein (α1PAG) were 1.86 ± 0.07 mg/ml, 0.12 ± 0.02 mg/ml and 18.32 ± 4.07 AU/ml respectively in control rats. Maximum concentrations of α1MG were found in heart, lung and spleen and lesser quantities were in liver and thymus, while α2MG and α1PAG were not found at all in tissue extracts from control rats

Topics: Original Articles
Publisher: Blackwell Science Inc
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Provided by: PubMed Central
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