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The value of immunoreactive lipase in acute pancreatitis.

By D. M. Hemingway, I. Johnson, D. J. Tuffnell and R. S. Croton


We have evaluated a new agglutination test for serum immunoreactive lipase in 24 patients with abdominal pain and hyperamylasaemia. On admission all 20 patients with acute pancreatitis had a positive lipase test, 3 of the 4 patients who did not have pancreatitis had a negative lipase test. The sensitivity of the lipase test on day 1 is 100%, the specificity 96% and predictive value of a positive test is 95.2% compared to 83% for amylase. A negative test excludes pancreatitis. In addition, the test stays positive longer than hyperamylasaemia

Topics: Research Article
Publisher: Royal College of Surgeons of England
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Provided by: PubMed Central
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