Location of Repository

Topical antiseptics in addition to peroperative antibiotics in preventing post-appendicectomy wound infections.

By R. B. Galland, T. Karlowski, C. J. Midwood, M. V. Madden and H. Carmalt

Abstract

The effect of using topical povidone-iodine spray in addition to a single dose of intravenous metronidazole was studied in a clinical trial involving 200 patients undergoing appendicectomy. Despite the metronidazole, patients with perforated or gangrenous appendices still had an unacceptably high rate of wound infection. Overall, no benefit resulted from the addition of the povidone-iodine spray. Sub-dividing the patients according to the macroscopic state of the appendix, the degree of bacterial contamination of the operative wound or the depth of subcutaneous fat also failed to reveal any advantage gained by using the antiseptic

Topics: Research Article
Publisher: Royal College of Surgeons of England
OAI identifier: oai:pubmedcentral.nih.gov:2494412
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.