Skip to main content
Article thumbnail
Location of Repository

Rapid detection of typhoid carriers by means of fluorescent antibody techniques*

By Berenice M. Thomason and Alma C. McWhorter


Fluorescent antibody techniques have proved advantageous for rapid detection of enteropathogenic Escherichia coli. Previous attempts to adapt these procedures to the rapid identification of Salmonella typhi have been limited by the number of cross-reactions obtained when a polyvalent Salmonella or a S. typhi O conjugate was used to stain faecal smears. The results obtained using a purified Vi conjugate and a S. typhi O, Vi conjugate to screen faecal smears from a number of typhoid carriers are described in this report. The data show that essentially the same number of carriers were found positive by fluorescent antibody as were found by conventional bacteriological methods, although each technique missed a number of positive specimens that were detected by the other. The immunofluorescent technique has the advantage of being more rapid and economical to perform than cultural procedures

Topics: Articles
OAI identifier:
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.