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Toxicities of certain larvicides to resistant and susceptible Aedes aegypti

By W. Klassen, W. J. Keppler and J. B. Kitzmiller


In a study of the toxicological characteristics of dieldrin-resistant and DDT-resistant strains of Aedes aegypti, combined with an evaluation of certain larvicides, 14 cyclodienes, 13 DDT-type compounds, 18 organophosphorus compounds, several carbamates and a number of other compounds were tested against larvae of A. aegypti. Telodrin and GC-9160 proved to be toxic against a highly dieldrin-resistant strain. Against highly DDT-resistant strains the toxicity of DDT could be enhanced by piperonyl butoxide, DMC or WARF, that of deutero-DDT by DMC, and that of methoxychlor by piperonyl butoxide. Prolan and Bulan were found to be slightly less effective than deutero-DDT against highly DDT-resistant strains. Among the more recent organophosphorus compounds found to exceed fenthion in toxicity are AC-52160, Stauffer N-2404, Folithion, Bayer 52957 and SD-7438. The effectiveness of dimethrin could be enhanced with piperonyl butoxide

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