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Immunoglobulin G Avidities in Infants in Mexico after Primary Immunization with Three Doses of Polyribosylribitol Phosphate-Tetanus Toxoid Haemophilus influenzae Type b Vaccine▿ †

By Patricia Gómez-de-León, F. Javier Díaz-García, Alberto Villaseñor-Sierra, Jorge Segura, Martha I. Carranza, José Luis Arredondo-Garcia and José Ignacio Santos


Serum immunoglobulin G concentrations and avidities specific to Haemophilus influenzae type b (Hib) were measured in 208 children living in Guadalajara and Mexico City. Protective concentrations were found in 98.9% and 100.0% of participants, respectively. Geometric mean concentrations differed between both populations and/or among age groups. Mean avidities differed only among the 7- to 12-month-old children. Diphtheria-tetanus-whole-cell pertussis-hepatitis B-Hib primary vaccination seems to induce protection in Mexican children

Topics: Vaccine Research
Publisher: American Society for Microbiology (ASM)
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Provided by: PubMed Central
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