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The Management of Persistent or Recurrent Variceal Bleeding After Injection Sclerotherapy by Somatostatin

By S. A. Jenkins, R. Shields, N. Jaser, S. Ellenbogen, E. Naylor and J. N. Baxter


Sixteen patients with persistent (n = 11) or recurrent (n = 5) variceal bleeding after injection sclerotherapy and balloon tamponade were treated with an intravenous infusion of somatostatin 250μg/ h. Somatostatin infusion successfully controlled the bleeding in 15 of the 16 patients but one rebled after 72 h of treatment. In one patient with poor liver function (Child’s C) bleeding was not controlled by somatostatin, further injection sclerotherapy or balloon tamponade of the oesophagus. The results of this study, although uncontrolled and with a small number of patients, suggest that somatostatin is a very effective treatment for the control of post-injection sclerotherapy variceal bleeding

Topics: Research Article
Publisher: Hindawi Publishing Corporation
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Provided by: PubMed Central
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    1. (1989). A comparison of sclerotherapy with staple transection of the esophagus for the emergency control of bleeding from oesophageal varices.
    2. (1988). Variceal haemorrhage after failed injection sclerotherapy: The role of emergency oesophageal transection.

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