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A rush to judgment on Th17

By Lawrence Steinman

Abstract

Some immunologists have characterized T helper (Th)17 T cells as the master mediators of tissue damage in a variety of pathological conditions. New data now demonstrate that Th1 and Th17 T cells are independently capable of inducing disease in two established models of autoimmunity. Thus, the role of Th17 cytokines as the central mediators of pathological tissue damage seems to require clarification

Topics: Commentaries
Publisher: The Rockefeller University Press
OAI identifier: oai:pubmedcentral.nih.gov:2442627
Provided by: PubMed Central
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