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Evidence of scrapie transmission via milk

By Timm Konold, S Jo Moore, Susan J Bellworthy and Hugh A Simmons
Topics: Research Article
Publisher: BioMed Central
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Provided by: PubMed Central

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  1. (2004). A review of behavioural and physiological responses of sheep to stressors to identify potential behavioural signs of distress. Anim Welfare
  2. (2005). Aguzzi A: PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nat Med
  3. (2007). Andréoletti O: Dynamics and genetics of PrPSc placental accumulation in sheep.
  4. (2006). Atypical prion protein in sheep brain collected during the British scrapie-surveillance programme.
  5. (2007). Classical sheep transmissible spongiform encephalopathies: pathogenesis, pathological phenotypes and clinical disease. Neuropathol Appl Neurobiol
  6. (2006). Comparative evidence for a link between Peyer's patch development and susceptibility to transmissible spongiform encephalopathies. BMC Infect Dis
  7. (2005). del Riego L, Torres JM: Vertical transmission of bovine spongiform encephalopathy prions evaluated in a transgenic mouse model.
  8. (2006). Di Guardo G: PrP(Sc) deposition in nervous tissues without lymphoid tissue involvement is frequently found in ARQ/ARQ Sarda breed sheep preclinically affected with natural scrapie. Arch Virol
  9. (2007). EFSA: Opinion on the quantitative risk assessment on the residual BSE risk in sheep meat and meat products.
  10. (2000). F: Early accumulation of PrP(Sc) in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie.
  11. (2002). FG: Early and late pathogenesis of natural scrapie infection in sheep. APMIS
  12. (2006). Flock-level risk factors for scrapie in Great Britain: analysis of a 2002 anonymous postal survey. BMC Vet Res
  13. (1961). GC: Experimental transmission of scrapie to goats and sheep by the oral route.
  14. (2005). Groschup MH: Highly bovine spongiform encephalopathy-sensitive transgenic mice confirm the essential restriction of infectivity to the nervous system in clinically diseased cattle. J Infect Dis
  15. (2000). Inactivation of transmissible degenerative encephalopathy agents: a review. Vet J
  16. (1991). JE: Somatic cell counts of ewes' milk.
  17. (1999). Laplanche JL: Genetic susceptibility and transmission factors in scrapie: detailed analysis of an epidemic in a closed flock of Romanov. Arch Virol
  18. Mastitis and contagious agalactia.
  19. (2007). MM: Immunohistochemistry for PrPSc in natural scrapie reveals patterns which are associated with the PrP genotype. Neuropathol Appl Neurobiol
  20. (1982). Natural infection of Suffolk sheep with scrapie virus.
  21. (2005). Natural transmission of BSE between sheep within an experimental flock. Vet Rec
  22. (2006). Postmortem diagnosis of preclinical and clinical scrapie in sheep by the detection of disease-associated PrP in their rectal mucosa. Vet Rec
  23. (1998). Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): an update. Vet Rec
  24. (2006). Prion protein in milk. PLoS One
  25. (2001). Ramanoon SZ: Mastitis of sheep and goats. Vet Clin North Am Food Anim Pract
  26. (2007). Rhind SM: Quantification of Peyer's patches in Cheviot sheep for future scrapie pathogenesis studies. Vet Immunol Immunopathol
  27. (2003). Scrapie and experimental BSE in sheep.
  28. (2007). Simmons MM: Clinical findings in two cases of atypical scrapie in sheep: a case report. BMC Vet Res
  29. Smits MA: Pathogenesis of natural scrapie in sheep.
  30. (2003). The epidemiology of scrapie. Rev Sci Tech
  31. (1983). The evolution and involution of Peyer's patches in fetal and postnatal sheep.
  32. (2004). Tongue S: Demonstration of lateral transmission of scrapie between sheep kept under natural conditions using lymphoid tissue biopsy. Res Vet Sci
  33. (2002). Transmission of prion diseases by blood transfusion.
  34. (2006). Ulvund MJ: Detection of PrP(Sc) in rectal biopsy and necropsy samples from sheep with experimental scrapie.
  35. (1984). Use of somatic cell counts for detection of subclinical mastitis in ewes. Vet Rec
  36. (1991). W: Untersuchungen über den Zellgehalt in Schaf- und Ziegenmilch [The cell count in sheep and goat milk]. Tierärztl Prax
  37. (2003). X: Mastitis of dairy small ruminants. Vet Res