Article thumbnail

Stroke in inflammatory bowel disease: a report of two cases and review of the literature

By Deepak Joshi, Tobias Dickel, Rakesh Aga and Gray Smith-Laing


Thrombosis is a recognised complication of inflammatory bowel disease (IBD), in particular venous thrombosis. Arterial thrombosis, especially stroke is rare. There is a paucity of information regarding stroke in IBD and its management. The authors describe two cases of stroke in patients with IBD during periods of increased disease activity. The literature regarding this devastating complication and the procoagulant state that exists in IBD are reviewed

Topics: Case Report
Publisher: BioMed Central
OAI identifier:
Provided by: PubMed Central

To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.

Suggested articles


  1. (2003). Activated platelets are the source of elevated levels of soluble CD40 ligand in the circulation of inflammatory bowel disease patients. Gut
  2. (2005). AF: Venous thrombosis in inflammatory bowel disease.
  3. (1992). Arterial thromboembolic complications of Inflammatory bowel disease. Diseases of the colon and rectum
  4. (1986). Beart RW: Vascular complications of inflammatory bowel disease. Mayo Clin Proc
  5. (1993). Caplan LR: Safety of anticoagulation in haemorrhagic infarctions. Neurology
  6. (1979). DM: Cerebral and retinal complications of inflammatory bowel disease. Ann Neurol
  7. (2004). DS: Formation of platelet leucocyte aggregates in inflammatory bowel disease. Inflammatory bowel disease
  8. (2005). DS: Thrombosis and inflammatory bowel disease. Clinical Gastroenterology and Hepatology
  9. (1978). Fahn S: Strokes and ulcerative colitis.
  10. (2004). G: Is IBD an independent risk factor for thromboembolism. Gut
  11. (2007). Inflammation and Coagulation in Inflammatory Bowel Disease: The Clot Thickens.
  12. (2004). Kouroumalis EA: Association between enhanced soluble CD40 ligand and prothrombotic state in inflammatory bowel disease. Eur J Gastro Hep
  13. (1993). Melkian V: Thromboembolism in IBD. Gut
  14. (2005). Soylu AR: Cerebral sinus thrombosis in patients with IBD: A case report. World Journal of gastroenterology
  15. (2004). SP: Guidelines for the management of inflammatory bowel disease in adults. Gut
  16. T: Haemorrhagic cerebral sinus thrombosis associated with ulcerative colitis: a case report of successful treatment by anticoagulant therapy.
  17. (2006). The search for a common thrombophilic state during the active state of inflammatory bowel disease.
  18. (2005). Therapy Insight: vascular complications in patients with inflammatory bowel disease.
  19. (2004). Trouillas P: Large artery stroke in a young patient with Crohn's disease. Role of vitamin B6 deficiencyinduced hyperhomocysteinaemia.
  20. (2004). Vogelsang H: Aortic mural thrombi in patients with Inflammatory bowel disease. Inflammatory bowel disease