Fluoroquinolone Resistance in Salmonella: A Web Discussion


ington, DC) was asked by Dr. Abigail Salyers, who runs the Reservoirs of Antibiotic Resistance (ROAR) web site, to com-ment on the article by Mùlbak et al. [1] published in the New England Journal of Medicine in November 1999. Dr. Salyers requested that the article in the New England Journal of Med-icine [1] be discussed, since it may have demonstrated a bridge to clinical impacts in humans from antibiotic-resistant bacteria in animals. Dr. Carnevale's Comments There are other researchers with far more expertise to judge the conclusions drawn by the authors, but it seems to me that the study falls short of clearly documenting that antibiotic use in animals was directly responsible for the deaths noted in the study. What the study showed was that food animals, in this case pigs, can be a source for Salmonella and, in particular, the DT10

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