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In Vitro Activity of the New Azole Isavuconazole (BAL4815) Compared with Six Other Antifungal Agents against 162 Cryptococcus neoformans Isolates from Cuba▿

By Maria-Teresa Illnait-Zaragozi, Gerardo F. Martínez, Ilse Curfs-Breuker, Carlos M. Fernández, Teun Boekhout and Jacques F. Meis


Cuban Cryptococcus isolates (n = 165) were tested in vitro against amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole, posaconazole, and isavuconazole, giving MIC90 values of 0.25, 8, 4, 0.25, 0.125, 0.016, and 0.016 μg/ml, respectively. Isavuconazole and posaconazole seem to be potentially active drugs for treating cryptococcal infections

Topics: Susceptibility
Publisher: American Society for Microbiology (ASM)
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Provided by: PubMed Central
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