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P15-T SameSpots: Validating a Novel Approach to 2D Electrophoresis Image Analysis

By I. Reah, M. O’Gorman, A. Borthwick, D. Miller and D. Bramwell

Abstract

2D-PAGE experiments can provide a powerful means of investigating protein expression behavior in a cell or tissue across different disease states or other experimental conditions. Traditional analysis of 2D experiments typically requires a large amount of post-detection editing in order to prepare the data for statistical research. With the application of SameSpots, all protein spots are fully matched and thus no missing values exist. This enables a more robust statistical exploration of the data with a reduction in subjective editing

Topics: Poster Abstracts: Bioinfomatics
Publisher: The Association of Biomolecular Resource Facilities
OAI identifier: oai:pubmedcentral.nih.gov:2291895
Provided by: PubMed Central
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