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Invited Commentary



“Evidence based medicine is the conscientious, explicit, and judicious use of current best evidence in making decisions about the care of individual patients.”1 Clearly, an attempt to apply the tenets of evidence-based medicine to the care of patients requires an understanding of what qualifies as “current, best evidence. ” In the practical world of patient care, decisions must often be made using best evidence as opposed to often unavailable definitive or “gold-standard ” evidence. Clinicians owe to patients the use of their best judgment and analysis to apply insightful, relevant, and informative data to care deci-sions. This is equally as necessary in preventive care as it is in therapeutic care settings. Evidenced obtain from prospective, randomized clinical tri-als (PRCTs) is generally recognized as gold standard, because PRCT methodology avoids many of the biases that creep int

Year: 2016
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