Article thumbnail

Genomic and phylogenetic perspectives on the evolution of prokaryotes

By James R. Brown


Abstract.—Prokaryoteshavebeenat the forefrontof the genomesequencing revolution.Manygenomes havebeencompletely sequenced, revealingmuchabout bacterial and archaeal genome content and or-ganization. Yet, a meaningful evolutionary picture of prokaryotes still eludes us. Much of the problem lies in understanding the mode and tempo of genome evolution. Here phenylalanyl-tRNA synthetase is used as an example of the complex interplay among lateral gene transfer, operon recombination, and gene recruitment in the evolution of some prokaryotic genes. Promising new approaches to genomic analyses, which could add to our understanding prokaryotic evolution and help in their classication, are discussed. [Archaea; comparative genomics; eubacteria; phenylalanyl-tRNA synthetase; universal tree.] An understanding of the evolutionary re-lationships among prokaryotes—the most abundant and diverse life forms on the planet—is essential. The important impact of prokaryotes on human health and economy as well as their key role in eukaryotic evolu

Year: 2001
DOI identifier: 10.1080/106351501750435068
OAI identifier: oai:CiteSeerX.psu:
Provided by: CiteSeerX
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://sysbio.oxfordjournals.o... (external link)
  • http://sysbio.oxfordjournals.o... (external link)
  • (external link)
  • Suggested articles

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.