Multimodal functional imaging investigation before and after the onset of psychosis

Abstract

Mr A. was a 20-yr-old white male with no medical history of note. His GP, who was concerned about his poor psychosocial functioning, referred him to a specialist service offering advice and support for young people at risk for psychosis. On assessment he reported daily paranoid exper-iences such as ‘sensing ’ the thoughts of strangers passing him on the street, next-door-neighbours and family members. He also reported occasional visual and tactile hallucinations. The frequency and severity of these symptoms did not reach DSM-IV criteria for schizophrenia or other psychotic disorders [Positiv

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