Location of Repository

Development of Chronic Bronchitis and Emphysema in β-Epithelial Na+ Channel–Overexpressing Mice

By Marcus A. Mall, Jack R. Harkema, Joanna B. Trojanek, Diana Treis, Alessandra Livraghi, Susanne Schubert, Zhe Zhou, Silvia M. Kreda, Stephen L. Tilley, Elizabeth J. Hudson, Wanda K. O'Neal and Richard C. Boucher

Abstract

Rationale: Chronic obstructive pulmonary disease is a leading cause of death worldwide, but its pathogenesis is not well understood. Previous studies have shown that airway surface dehydration in β-epithelial Na+ channel (βENaC)–overexpressing mice caused a chronic lung disease with high neonatal pulmonary mortality and chronic bronchitis in adult survivors

Topics: C. Chronic Obstructive Pulmonary Disease
Publisher: American Thoracic Society
OAI identifier: oai:pubmedcentral.nih.gov:2277210
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles


    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.