Location of Repository

Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish

By Cornelia Stein, Mario Caccamo, Gavin Laird and Maria Leptin


Analysis of several fish genomes reveals components of the innate immune system and identifies orthologous relationships between gene families of fish and mammals

Topics: Research
Publisher: BioMed Central
OAI identifier: oai:pubmedcentral.nih.gov:2258186
Provided by: PubMed Central
Download PDF:
Sorry, we are unable to provide the full text but you may find it at the following location(s):
  • http://www.pubmedcentral.nih.g... (external link)
  • Suggested articles



    1. (2004). AC: Conservation, duplication and divergence of the zebrafish stat5 genes. Gene
    2. (2003). Albuquerque A: Atlantic salmon interferon genes: cloning, sequence analysis, expression, and biological activity.
    3. (2006). An unexpected discovery of two interferon gamma-like genes along with interleukin (IL)-22 and -26 from teleost: IL-22 and -26 genes have been described for the first time outside mammals. Mol Immunol
    4. (2000). Aravind L: The NACHT family: a new group of predicted NTPases implicated in apoptosis and MHC transcription activation. Trends Biochem Sci
    5. (2002). Aravind L: The role of lineagespecific gene family expansion in the evolution of eukaryotes. Genome Res
    6. (2007). CH: Evidence for evolving Toll-IL-1 receptor-containing adaptor molecule function in vertebrates.
    7. (2003). CH: Molecular and functional analysis of an interferon gene from the zebrafish, Danio rerio.
    8. (2006). Cheng G: Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature
    9. (2006). Chinchar VG: Identification and expression analysis of cDNAs encoding channel catfish type I interferons. Fish Shellfish Immunol
    10. (2006). Chinchar VG: Identification and expression analysis of interferon gamma genes in channel catfish. Immunogenetics
    11. (2004). Chinchar VG: Identification of a cDNA encoding channel catfish interferon. Dev Comp Immunol
    12. (2003). Chinchar VG: Molecular identification and expression analysis of tumor necrosis factor in channel catfish (Ictalurus punctatus). Dev Comp Immunol
    13. (2005). Chong SS: Genomic, cDNA and embryonic expression analysis of zebrafish IRF6, the gene mutated in the human oral clefting disorders Van der Woude and popliteal pterygium syndromes. Gene Expr Patterns
    14. (2003). Class II cytokine receptors and their ligands: key antiviral and inflammatory modulators. Nat Rev Immunol
    15. (2005). CM: Organization and promoter analysis of the zebrafish (Danio rerio) interferon gene.
    16. (2006). Ensembl 2006. Nucleic Acids Res
    17. (2003). Evolution and diversity of fish genomes.
    18. (2005). Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives. Pharmacol Ther
    19. (2007). Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Science
    20. (2004). Ewa Snaar-Jagalska B, Spaink HP: Expression analysis of the Tolllike receptor and TIR domain adaptor families of zebrafish. Mol Immunol
    21. (2001). FW: Molecular cloning and expression of a TNF receptor and two TNF ligands in the fish ovary.
    22. (2005). Genome evolution and biodiversity in teleost fish. Heredity
    23. (2004). GJ: The Jalview Java alignment editor. Bioinformatics
    24. GW: Immune-type receptor genes in zebrafish share genetic and functional properties with genes encoded by the mammalian leukocyte receptor cluster.
    25. (2006). JA: Immune-related, lectin-like receptors are differentially expressed in the myeloid and lymphoid lineages of zebrafish. Immunogenetics
    26. (2001). JA: Novel immune-type receptor genes. Immunol Rev
    27. (2004). JC: Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses.
    28. (2006). Kimura A: Genomic view of the evolution of the complement system. Immunogenetics
    29. (1990). Lipman DJ: Basic local alignment search tool.
    30. (2006). Litman GW: Genomic insights into the immune system of the sea urchin. Science
    31. (1999). Lutfalla G: Comparative genomic analysis of the interferon/interleukin-10 receptor gene cluster. Genome Res
    32. (2007). Lutfalla G: Identification of the zebrafish IFN receptor: implications for the origin of the vertebrate IFN system.
    33. (2006). Meijer AH: MyD88 innate immune function in a zebrafish embryo infection model. Infect Immun
    34. (2003). Monneron D: Comparative genomic analysis reveals independent expansion of a lineage-specific gene family in vertebrates: the class II cytokine receptors and their ligands in mammals and fish.
    35. (2004). Nei M: MEGA3: Integrated software for molecular evolutionary genetics analysis and sequence alignment. Brief Bioinform
    36. (1998). Profile hidden Markov models. Bioinformatics
    37. (2004). Resolution of the novel immune-type receptor gene cluster in zebrafish.
    38. (2004). S: HMM Logos for visualization of protein families.
    39. (2005). Secombes C: Identification and bioactivities of IFN-gamma in rainbow trout Oncorhynchus mykiss: the first Th1-type cytokine characterized functionally in fish.
    40. (2004). Secombes C: Identification of an interferon gamma homologue in Fugu, Takifugu rubripes. Fish Shellfish Immunol
    41. (2003). Secombes CJ: Characterisation, expression and promoter analysis of an interleukin 10 homologue in the puffer fish, Fugu rubripes. Immunogenetics
    42. (2007). Secombes CJ: Identification of a second group of type I IFNs in fish sheds light on IFN evolution in vertebrates.
    43. (2005). SG: Cloning, characterization and expression analysis of interleukin-10 from the zebrafish (Danio rerio).
    44. (2005). Spatial and temporal distribution of the traf4 genes during zebrafish development. Gene Expr Patterns
    45. (2007). TC: The innate immune repertoire in cnidaria - ancestral complexity and stochastic gene loss. Genome Biol
    46. (2006). The immune gene repertoire encoded in the purple sea urchin genome. Dev Biol
    47. (1998). The NB-ARC domain: a novel signalling motif shared by plant resistance gene products and regulators of cell death in animals. Curr Biol
    48. (1987). The neighbor-joining method: a new method for reconstructing phylogenetic trees. Mol Biol Evol
    49. (2001). The Zebrafish Information Network (ZFIN): a resource for genetic, genomic and developmental research. Nucleic Acids Res
    50. (1994). TJ: CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res
    51. (2006). Toll-like receptor 3 and TICAM genes in catfish: species-specific expression profiles following infection with Edwardsiella ictaluri. Immunogenetics
    52. (2004). Toll-like receptor gene family and TIR-domain adapters in Danio rerio. Mol Immunol
    53. (2003). Trede NS: The zebrafish as a model organism to study development of the immune system. Adv Immunol
    54. (2002). Verburg-van Kemenade BM: Neuroendocrineimmune interactions in fish: a role for interleukin-1. Vet Immunol Immunopathol
    55. (2004). Verburg-van Kemenade BM: The molecular evolution of the interleukin-1 family of cytokines; IL-18 in teleost fish. Dev Comp Immunol
    56. (2004). Zon LI: The use of zebrafish to understand immunity. Immunity

    To submit an update or takedown request for this paper, please submit an Update/Correction/Removal Request.